Effect of third ventricular injection of beta-endorphin on the electrophysiological responses of some regions of endocrine hypothalamus.
Indian J Physiol Pharmacol
;
1985 Apr-Jun; 29(2): 75-82
Artigo
em Inglês
| IMSEAR
| ID: sea-106563
ABSTRACT
Multiunit activity (MUA) of arcuate nucleus and cortical EEG were recorded in the regularly cycling female rats on the day of proestrous under urethane anaesthesia. The MUA was compared before and after injection of beta-endorphin in third ventricle. In some animals MUA increased after 30-40 min and persisted for 3-4 hr, in others MUA got inhibited within 5-10 min of injection of beta-Endorphin and effect lasted for 5-6 hr. There was no change in frontoparietal EEG activity. In another group of animals medial pre-optic responses (MPO) to stimulation of medial amygdala were tested before and after ventricular infusion of beta-endorphin. Most of the facilitatory MPO responses got blocked. These observations suggest the involvement of opioid receptors in the mediation of neuroendocrine control of preovulatory events through the amygdalo-preoptico-medial basal hypothalamic axis. There seems to be heterogeneity of beta-endorphin receptors in the arcuate nucleus.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Fatores de Tempo
/
Núcleo Arqueado do Hipotálamo
/
Feminino
/
Beta-Endorfina
/
Endorfinas
/
Eletroencefalografia
/
Eletrofisiologia
/
Hipotálamo
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1985
Tipo de documento:
Artigo
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