Phagocytic response of leucocytes in secretors and non-secretors of ABH (O) blood group substances.

ABSTRACT

Secretor status of healthy young volunteers in the age group of 18-22 years and having similar socio-economic background was determined by standard agglutination inhibition test of the saliva. Phagocytic response of leucocyte was worked out by in vitro suspension technique and average number of cocci engulfed by leucocytes calculated in secretors/non-secretors of each blood group. Leucocytes of non-secretors of O and AB seem to have more and highly significant ingestion power as compared to secretors. Non secretors in group A & B also show more phagocytic activity. Relatively different concentration of the components of the blood group substances in secretors/non-secretors seems to affect phagocytic activity of the leucocytes.