Immobilisation stress induced analgesia in diabetic rats.
Indian J Physiol Pharmacol
;
1997 Jul; 41(3): 275-9
Artigo
em Inglês
| IMSEAR
| ID: sea-106696
ABSTRACT
Stress is known to produce analgesia. The pain threshold is altered in diabetes. We studied the effect of 1 hr of immobilisation stress on pain threshold in male Wistar rats. The same effect was tested in streptozotocin induced diabetic rats. The pain threshold of tail flick, vocalisation and vocalisation after discharge increased in the control group after the stress procedure. Significant analgesia was also obtained in diabetic rats, for flick and after discharge pain threshold. However the vocalisation threshold was not altered, probably due to the antagonistic action of glucose on opiate receptor at the level of brain stem.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Estresse Fisiológico
/
Vocalização Animal
/
Glicemia
/
Tronco Encefálico
/
Masculino
/
Ratos Wistar
/
Limiar da Dor
/
Estreptozocina
/
Receptores Opioides
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1997
Tipo de documento:
Artigo
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