Lipid peroxidation and antioxidant status in patients with diabetic retinopathy.
Indian J Physiol Pharmacol
;
2005 Apr; 49(2): 187-92
Artigo
em Inglês
| IMSEAR
| ID: sea-106698
ABSTRACT
Non Insulin Dependent Diabetes Mellitus is responsible for 60% cases of retinopathy in the population and is one of the common cause of blindness. Oxidative stress as measured by the levels of malondialdehyde, superoxide dismutase (SOD), glutathione peroxidase (GPx) and vitamin C was measured in 50 normal controls, 40 diabetics without complications, 22 diabetics with proliferative and 20 with nonproliferative retinopathy respectively. Our finding suggests that lipid peroxidation increases (P < 0.001) with the increase in severity and duration of diabetes. Antioxidants SOD and vitamin C decrease with the progression of the disease, however GPx tends to increase in the later part of the disease.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ácido Ascórbico
/
Superóxido Dismutase
/
Feminino
/
Humanos
/
Masculino
/
Peroxidação de Lipídeos
/
Estudos de Casos e Controles
/
Estresse Oxidativo
/
Adulto
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
2005
Tipo de documento:
Artigo
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