Changes in the activity of some hepatic enzymes during organophosphorus insecticide-acephate (orthene) treatment in albino rats.
Indian J Physiol Pharmacol
;
1982 Oct-Dec; 26(4): 311-6
Artigo
em Inglês
| IMSEAR
| ID: sea-106769
ABSTRACT
Acephate, an organophosphorus insecticide (60 mg/day/rat) disturbed the carbohydrate metabolism in albino rats (wt. between 100-150 gms). Changes in the enzyme activities in the liver were estimated in the rats after oral administration of Acephate. The specific activities of succinic dehydrogenase was decreased in experimental rats than control. A gradual decrease in blood and liver glutathione was also observed. Increase in total lactate dehydrogenase was also noted. It has been observed that in the liver homogenate of treated rats, the isoenzymes LDH4+5 were increased, LDH1+2 were decreased while LDH3 remain unchanged with respect to control value.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Compostos Organotiofosforados
/
Ratos
/
Succinato Desidrogenase
/
Feminino
/
Masculino
/
Glutationa
/
Inseticidas
/
L-Lactato Desidrogenase
/
Fígado
/
Animais
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1982
Tipo de documento:
Artigo
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