Effect of glucose on stress induced antinociception in normal mice.
Indian J Physiol Pharmacol
;
1998 Jan; 42(1): 131-4
Artigo
em Inglês
| IMSEAR
| ID: sea-106781
ABSTRACT
Stress induced analgesia has been shown to utilise both non-opioidergic and opioidergic mechanisms. Earlier studies indicate that opiodergic analgesics exhibit corollary changes in blood glucose level. In this study, the changes in blood glucose level by swim induced stress and the influence of exogenous glucose administration on the stress induced antinociception were studied. Stress per se (both 30 sec and 3 min) did not modify the blood glucose level. However, exogenous administration of glucose reversed the stress induced antinociception in both non-opioid and opioid segments. Our results favour a role for glucose in stress induced analgesic activity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Dor
/
Estresse Psicológico
/
Natação
/
Glicemia
/
Masculino
/
Receptores Opioides
/
Glucose
/
Analgesia
/
Animais
/
Camundongos
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1998
Tipo de documento:
Artigo
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