Effect of Mn++ on blood sugar level in rats.
Indian J Physiol Pharmacol
;
1982 Jul-Sep; 26(3): 227-30
Artigo
em Inglês
| IMSEAR
| ID: sea-107056
ABSTRACT
Mn++ produced hypoglycemia in normal rats. The effect was dose-dependent. However, Mn++ did not produce hypoglycemia in alloxan-treated rats. There was a rise in liver glycogen following Mn++ treatment which was correlated with fall in blood sugar at 1 1/2 and 3 hr. There was also increase in the glucose uptake by rat diaphragm upto 47% between 2 and 3 hr. The results suggest that functioning, intact pancreatic beta-cells are necessary for the action of Mn++ and that Mn++ may have a peripheral effect on glucose entry into the cells.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Glicemia
/
Feminino
/
Masculino
/
Diafragma
/
Diabetes Mellitus Experimental
/
Glucose
/
Hipoglicemia
/
Glicogênio Hepático
/
Animais
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1982
Tipo de documento:
Artigo
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