Subacute toxicity study of the combination of ginseng (Panax ginseng) and ashwagandha (Withania somnifera) in rats: a safety assessment.
Indian J Physiol Pharmacol
;
1998 Apr; 42(2): 299-302
Artigo
em Inglês
| IMSEAR
| ID: sea-107302
ABSTRACT
Ginseng (Panax ginseng) and Ashwagandha (Withania somnifera) are widely used as geriatric tonics. Both individually have not shown any toxicity on long term administration. Study was planned to assess the safety of the combination by doing subacute toxicity study in rats with 90 days oral administration using three doses. Food consumption, body weight, haematological, biochemical and histopathological parameters were studied. There was significant increase in body weight, food consumption and liver weight, and improved hematopoiesis was observed. Brain, heart, lung, liver, spleen, kidneys, stomach, testis and ovaries were normal on gross examination and histopathologically. Subacute toxicity studies in rats did not reveal any toxicity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamanho do Órgão
/
Plantas Medicinais
/
Ratos
/
Feminino
/
Masculino
/
Hemoglobinas
/
Extratos Vegetais
/
Aumento de Peso
/
Anti-Inflamatórios não Esteroides
/
Administração Oral
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1998
Tipo de documento:
Artigo
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