Toxicological study of Semecarpus anacardium nut extract.
Indian J Physiol Pharmacol
;
1979 Apr-Jun; 23(2): 115-20
Artigo
em Inglês
| IMSEAR
| ID: sea-107457
ABSTRACT
Toxicological study was carried out in rats with chloroform-soluble fraction of the nuts of Semecarpus anacardium to determine its safe non-toxic dose. The fraction produced toxicity at all levels tested (50-400 mg/kg) but the extent of toxicity was found dose-dependent. At lower doses this fraction induced partial growth inhibition over 36 days and higher doses proved fatal within 6 days. It was observed that 230 mg/kg caused 50% mortality in rats and this value is 1380 mg/m2 when expressed for body surface area. This work will be of some use in the cancer chemotherapy study of the fraction.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plantas Medicinais
/
Ratos
/
Fatores de Tempo
/
Comportamento Animal
/
Peso Corporal
/
Masculino
/
Extratos Vegetais
/
Dose Letal Mediana
/
Animais
/
Nozes
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1979
Tipo de documento:
Artigo
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