Regional metabolism of 5-hydroxytryptamine in brain under acute and chronic heat stress.
Indian J Physiol Pharmacol
;
1993 Jan; 37(1): 8-12
Artigo
em Inglês
| IMSEAR
| ID: sea-107604
ABSTRACT
The metabolic alteration of 5-HT in four different regions of rat brain and plasma was studied under acute and chronic heat stress. A generalised elevation of 5-HT in all the brain regions along with high plasma level was observed in animals subjected to 4 hour heat stress at 38 degrees C. Such elevation of brain 5-HT may be due to entry of plasma 5-HT into the brain owing to breakdown of blood-brain barrier (BBB). In heat adapted rats, where BBB remained unaffected, no increase in brain 5-HT was observed, rather a significantly low level was maintained both in plasma and brain tissue.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Estresse Fisiológico
/
Encéfalo
/
Feminino
/
Masculino
/
Adaptação Fisiológica
/
Barreira Hematoencefálica
/
Serotonina
/
Doença Aguda
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1993
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS