Effect of catechin on intestinal lipid metabolism.
Indian J Physiol Pharmacol
;
1998 Apr; 42(2): 286-90
Artigo
em Inglês
| IMSEAR
| ID: sea-107666
ABSTRACT
On analysing the effect of catechin on intestinal lipid metabolism, an increase in the concentration of cholesterol in the duodenum and jejunum was observed along with an increase in the HMGCoA reductase activity. In the in vitro experiments also it was found that cholesterol and free fatty acid (FFA) levels were increased in these two regions. Binding of catechin with cholesterol in the lumen, reduces the availability of cholesterol for absorption which may in turn stimulate cholesterol biosynthesis and a rise in the HMGCoA reductase activity. These alterations produced by catechin may also be related to the degradation of cholesterol to bile acids, as endogenous cholesterol is the preferred substrate for bile acid synthesis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fosfolipídeos
/
Ratos
/
Triglicerídeos
/
Masculino
/
Radioisótopos de Carbono
/
Catequina
/
Colesterol
/
Ratos Sprague-Dawley
/
Metabolismo dos Lipídeos
/
Glucose
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1998
Tipo de documento:
Artigo
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