Evidence for melanin concentrating hormone (MCH) receptors mediating melanosome aggregation in Labeo melanophores.
Indian J Physiol Pharmacol
;
1990 Jul; 34(3): 187-90
Artigo
em Inglês
| IMSEAR
| ID: sea-107816
ABSTRACT
Melanin concentrating hormone (MCH 5 x 10(-12)-5 x 10(-8) M) induced a concentration related, rapid and reversible pigment aggregation in innervated melanophores of Labeo rohita. In inducing melanosome aggregation MCH was found to be 10(4) times more potent than norepinephrine. Experiments employing phentolamine and propranolol suggest that MCH acts through its own specific receptors on the melanophores unrelated to adrenoceptors. MCH was able to aggregate the melanosomes even in the absence of extracellular Ca2+.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fentolamina
/
Hormônios Hipofisários
/
Propranolol
/
Pele
/
Carpas
/
Norepinefrina
/
Agregação Celular
/
Cálcio
/
Receptores de Superfície Celular
/
Hormônios Hipotalâmicos
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1990
Tipo de documento:
Artigo
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