Comparative assessment of pedal pressing rates of self-stimulation of hypothalamus and midbrain with both square wave and sine wave stimulus parameters.
Indian J Physiol Pharmacol
;
1990 Jul; 34(3): 162-70
Artigo
em Inglês
| IMSEAR
| ID: sea-107879
ABSTRACT
In Wistar rats, the regional differences of pedal pressing rates of self-stimulation (SS) of lateral hypothalamus (LH) and substantia nigra-ventral tegmental area (SN-VTA) were assessed with electrodes implanted in both regions in each subject. Average of SS rates of SN-VTA sites was significantly higher than that of LH sites, tested with both sine wave and square wave types of stimuli. There was no significant difference in SS rates between males and females, and also in the females between different days of oestrus cycles. The high rates of robust SS observed in this study relative to SS rates reported in past literature were probably due not only to the placements of electrodes in the main substrates of SS, but also to the parameters of stimulus used (0.25 sec trains of sine waves through bipolar electrodes).
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Autoestimulação
/
Feminino
/
Masculino
/
Estro
/
Mesencéfalo
/
Substância Negra
/
Fatores Sexuais
/
Eletrodos Implantados
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1990
Tipo de documento:
Artigo
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