Evaluation of hepatoprotective activity of Ginkgo biloba in rats.
Indian J Physiol Pharmacol
;
2002 Apr; 46(2): 167-74
Artigo
em Inglês
| IMSEAR
| ID: sea-108097
ABSTRACT
The mechanism of hepatoprotective effects of Ginkgo biloba (GB), an herbal preparation with wide variety of therapeutic application, on paracetamol (Pcml) induced hepatic damage in rats has been investigated. GB treatment restored the marker enzyme levels indicating the in vivo protective effects against Pcml induced liver damage both in preventive and curative aspects. GB also reversed the increased TBARS levels, and elevated the GSH content of the liver. The results obtained from the study indicate hepatoprotective nature of GB, which might be due to its ability to prevent lipid peroxidation and replenishing the gllutathione level. The effects of GB were comparable to that of silymarin.
Texto completo:
DisponíveL
Índice:
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Assunto principal:
Ratos
/
Masculino
/
Extratos Vegetais
/
Ratos Wistar
/
Folhas de Planta
/
Ginkgo biloba
/
Avaliação Pré-Clínica de Medicamentos
/
Fígado
/
Animais
/
Fitoterapia
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
2002
Tipo de documento:
Artigo
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