Cerebral oedema and blood-brain and blood-CSF barriers in experimental brain trauma: effect of indomethacin-A prostaglandin synthetase inhibitor.
Indian J Physiol Pharmacol
;
1980 Apr-Jun; 24(2): 91-6
Artigo
em Inglês
| IMSEAR
| ID: sea-108164
ABSTRACT
Cerebral oedema often occurs following trauma to the brain. Recently several biogenic amines have been suggested for their possible mediation in the pathophysiology of traumatic brain oedema. The present investigation indirectly indicates that prostaglandins of E series are also involved in the etiology of cerebral oedema, since administration of a potent PG synthetase inhibitor, indomethacin significantly diminished oedematous swelling of traumatised rat brain.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamanho do Órgão
/
Prostaglandinas E
/
Ratos
/
Edema Encefálico
/
Lesões Encefálicas
/
Feminino
/
Masculino
/
Barreira Hematoencefálica
/
Permeabilidade da Membrana Celular
/
Córtex Cerebral
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1980
Tipo de documento:
Artigo
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