Effect of adenosine and inosine on carbon tetrachloride-induced liver damage in rats.
Indian J Physiol Pharmacol
;
1992 Jan; 36(1): 39-42
Artigo
em Inglês
| IMSEAR
| ID: sea-108223
ABSTRACT
Liver damage induced in rats by carbon tetrachloride (CCL4) was obvious macroscopically as well as microscopically in stained sections. Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma glutamyl transpeptidase (gamma-GT) were also significantly raised. Adenosine and inosine effectively countered the damage when these were given before and during the period during which CCl4 produces the typical damage. The beneficial effect was seen in biochemical as well as pathological studies.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Aspartato Aminotransferases
/
Ratos
/
Ratos Endogâmicos
/
Masculino
/
Intoxicação por Tetracloreto de Carbono
/
Adenosina
/
Alanina Transaminase
/
Gama-Glutamiltransferase
/
Hemorragia
/
Inosina
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1992
Tipo de documento:
Artigo
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