Gating of the dorsal penile nerve inputs by norepinephrine at the medial preoptic area in rats.
Indian J Physiol Pharmacol
;
2005 Jul-Sep; 49(3): 325-30
Artigo
em Inglês
| IMSEAR
| ID: sea-108355
ABSTRACT
The medial preoptic area neurons related to male sexual behaviour in rats were identified by their responses to dorsal penile nerve stimulation. These neurons were further tested with norepinephrine applied iontophoretically. From the 21 medial preoptic area neurons recorded in urethane anaesthetized rats, 17 neurons responded to dorsal penile nerve stimulation. Excitatory and inhibitory responses were found in almost equal number of neurons. 14 neurons responded to norepinephrine application, out of which six neurons were excited and eight were inhibited. The direction of changes produced by dorsal penile nerve stimulation and norepinephrine application were similar in 10 neurons. The results suggest that the sensory inputs from the genitalia are possibly gated by norepinephrine at the level of the medial preoptic area. Afferent information from the genitalia carried by dorsal penile nerve and the availability of norepinephrine at the level of the medial preoptic area probably help in maintaining adequate level of sexual arousal.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pênis
/
Área Pré-Óptica
/
Ratos
/
Potenciais de Ação
/
Masculino
/
Norepinefrina
/
Vias Aferentes
/
Iontoforese
/
Ratos Wistar
/
Estimulação Elétrica
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
2005
Tipo de documento:
Artigo
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