Cardiovascular effects of acetaldehyde in guinea pigs.
Indian J Physiol Pharmacol
;
1981 Jul-Sep; 25(3): 246-52
Artigo
em Inglês
| IMSEAR
| ID: sea-108373
ABSTRACT
The hemodynamic effects of intravenous administration of acetaldehyde were determined in anesthetized control (group I), propranolol pretreated (group II) and phentolamine pretreated (group III) guinea pigs. Acetaldehyde produced an immediate and significant increase in mean arterial pressure followed by its progressive decrease resulting in hypotension. Heart rate increased significantly. In propranolol treated animals, acetaldehyde-induced tachycardia was not produced whereas in phentolamine treated animals, the initial pressor response was converted into a depressor one. Hence the increase in mean arterial pressure and heart rate produced by acetaldehyde are likely to be due to catecholamine release from adrenergic nerve endings.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fentolamina
/
Propranolol
/
Pressão Sanguínea
/
Feminino
/
Masculino
/
Eletrocardiografia
/
Cobaias
/
Frequência Cardíaca
/
Hemodinâmica
/
Acetaldeído
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1981
Tipo de documento:
Artigo
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