Effect of co-administration of cassava (Manihot esculenta Crantz) rich diet and alcohol in rats.
Indian J Physiol Pharmacol
;
2004 Jan; 48(1): 41-50
Artigo
em Inglês
| IMSEAR
| ID: sea-108570
ABSTRACT
The effects of co-administration of a cassava rich diet and alcohol in rats were investigated. The animals were divided into four groups (1) Control, (2) Alcohol, (3) Cassava and (4) Alcohol + Cassava. Consumption of alcohol along with cassava reduced the alcohol induced toxicity which was evidenced by the lower activities of GOT, GPT, GGT, acid phosphatase and alkaline phosphatase in the liver and serum of co-administered group. The pyruvate content in the blood increased while the lactate content, lactate/pyruvate ratio and the activity of LDH decreased in the blood due to co-administration. The blood cyanide content, serum thiocyanate content and the activities of rhodanase and beta-glucuronidase increased on co-administration. The histopathological studies also revealed that co-administration reduced the alcohol induced toxicity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Aspartato Aminotransferases
/
Ratos
/
Tiocianatos
/
Fosfatase Ácida
/
Masculino
/
Manihot
/
Ratos Sprague-Dawley
/
Ácido Láctico
/
Ácido Pirúvico
/
Cianetos
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
2004
Tipo de documento:
Artigo
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