Uterotropic effect of clofibrate and phenylbutazone in immature female rats.
Indian J Physiol Pharmacol
;
1982 Apr-Jun; 26(2): 147-51
Artigo
em Inglês
| IMSEAR
| ID: sea-108729
ABSTRACT
The uterotropic effect of clofibrate and phenylbutazone was studied in immature female rats. A significant increase in the uterine wet weight was observed following clofibrate and phenylbutazone administration. Clofibrate but not phenylbutazone synergized with the uterotropic effect of ethinyl-oestradiol. Phenylbutazone pretreatment significantly decreased the pentobarbitone sleeping time. The uterotropic effect of clofibrate and phenylbutazone might involve displacement of 17-beta oestradiol (or ethinyl oestradiol) from plasma albumin binding sites in rats.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamanho do Órgão
/
Pentobarbital
/
Ratos
/
Sono
/
Útero
/
Feminino
/
Fenilbutazona
/
Clofibrato
/
Sinergismo Farmacológico
/
Estrogênios
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1982
Tipo de documento:
Artigo
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