Biochemical and pathological changes in response to hyperoxia and protection by antioxidants in rats.
Indian J Physiol Pharmacol
;
1992 Apr; 36(2): 97-100
Artigo
em Inglês
| IMSEAR
| ID: sea-108833
ABSTRACT
A significant decrease in blood haemoglobin, reduced glutathione and protein in lung and liver, without any change in blood reduced glutathione, was observed in rats exposed to 80% oxygen. Hydrogen peroxide induced erythrocyte haemolysis was significantly increased following exposure to hyperoxia. The lungs of rats exposed to hyperoxia showed perivascular edema. Simultaneous treatment with antioxidants, vitamin A, C, or E, protected the animals against oxygen toxicity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Oxigênio
/
Ácido Ascórbico
/
Ratos
/
Ratos Endogâmicos
/
Vitamina A
/
Vitamina E
/
Masculino
/
Hemoglobinas
/
Proteínas
/
Glutationa
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1992
Tipo de documento:
Artigo
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