Influence of calcium removal from bath solution on isolated rat duodenum contractions.
Indian J Physiol Pharmacol
;
1992 Jul; 36(3): 181-4
Artigo
em Inglês
| IMSEAR
| ID: sea-108988
ABSTRACT
In this study whether extracellular Ca++ is essential to produce an increase of tension of isolated rat duodenum by ACh, 5-HT, AVP and KCl-, was examined. KCl- and AVP-evoked contractions were almost totally prevented by Ca++ removal from bath solution. The increase of tension of isolated duodenum caused by ACh or 5-HT was totally prevented after adding nifedipine, a Ca++ channel blocker, into Ca free solution. Our results suggest that ACh or 5-HT utilizes intracellular as well as extracellular sources of Ca++ to produce contraction in rat duodenum, whereas AVP-or KCl evoked contraction was mainly due to influx of Ca from extracellular sources.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Cloreto de Potássio
/
Ratos
/
Arginina Vasopressina
/
Nifedipino
/
Acetilcolina
/
Serotonina
/
Cálcio
/
Duodeno
/
Animais
/
Contração Muscular
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1992
Tipo de documento:
Artigo
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