Influence of cigarette smoking on Vitamin C, glutathione and lipid peroxidation status.
Indian J Public Health
;
1998 Jan-Mar; 42(1): 20-3
Artigo
em Inglês
| IMSEAR
| ID: sea-109277
ABSTRACT
There has been a growing interest during recent years in the role of free radicals and lipid-peroxidation at tissue-level for the causation of cancer and other age-related diseases like atherosclerosis, rheumatoid arthritis, cataract etc. Free radicals and increased lipid peroxidation play a significant role for causation of human diseases by oxidative damage and functional degeneration of the tissues. Vitamin C, a well-known dietary antioxidant, and other enzymatic antioxidants like glutathione can protect the lipids of lipoproteins and other biomembranes against peroxidative damage by intercepting oxidants before they can attack the tissues. But cigarette smoking was found to affect the antioxidant protective action of Vitamin C, glutathione etc. A group of adult male smokers in this study were found to have lowered Vitamin 'C' & glutathione levels, but increased lipid-peroxide levels in their blood. Thus the increased pathogenicity of the smoking may also be due to indirect biochemical effect of enhanced oxidative stress by increased lipid-peroxidation and lowered Vitamin C & other antioxidants at tissue-level.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ácido Ascórbico
/
Humanos
/
Masculino
/
Peroxidação de Lipídeos
/
Fumar
/
Estudos de Casos e Controles
/
Adulto
/
Glutationa
/
Antioxidantes
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Public Health
Ano de publicação:
1998
Tipo de documento:
Artigo
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