Impact of Toombak dipping in the etiology of oral cancer: gender-exclusive hazard in the Sudan.
J Cancer Res Ther
;
2007 Apr-Jun; 3(2): 127-30
Artigo
em Inglês
| IMSEAR
| ID: sea-111371
ABSTRACT
BACKGROUND:
Oral cancer (OC) mortality is very high in Sudan, particularly among men due to the habit of Toombak use (tobacco specific nitrose amine (TSN)) rich tobacco.AIMS:
Our aim was to determine whether OC is gender-specific due to increased Toombak use among males as suggested a risk for subsequent development of oral cancer. SETTINGS ANDDESIGN:
We conducted a descriptive study of OC in Khartoum and obtained information on Toombak use, confounding variables for 39 incident patients with oral cancerous lesions and 43 hospital-based cases without apparent oral lesions. MATERIALS ANDMETHODS:
OC was affirmed by histopathology for all patients with oral lesions, hence oral epithelial atypia and leukoplakias were detected using cytology. STATISTICALANALYSIS:
Data analyzed using a computer SPSS program. RESULTS ANDCONCLUSIONS:
Of the 82 subjects, there were 57 (70%) Toombak users and 25 (30%) non-tobacco users. Among the 39 patients with OC, 24 (61.5%) were Toombak users and 15 (38.5%) were non-tobacco users. Among 43 with atypical changes, 10 (23.3%) were non-tobacco users and 33 (76.7%) were Toombak users. Regarding gender, only 11 (13.4%) were females, of whom 8 (72.7%) were non-tobacco users. We conclude that oral cancer, atypia and leukoplakia were high among males who were Toombak users. In view of the high incidence (29%) of OC due to Toombak use, we propose the implementation of oral screening programme restricted to Toombak users.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sudão
/
Feminino
/
Humanos
/
Masculino
/
Neoplasias Bucais
/
Fatores de Risco
/
Adolescente
/
Tabaco sem Fumaça
/
Adulto
/
Pessoa de Meia-Idade
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
País/Região como assunto:
África
Idioma:
Inglês
Revista:
J Cancer Res Ther
Assunto da revista:
Neoplasms
/
Therapeutics
Ano de publicação:
2007
Tipo de documento:
Artigo
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