Magnetic resonance imaging in carcinoma cervix--does it have a prognostic relevance.
J Cancer Res Ther
;
2005 Apr-Jun; 1(2): 103-7
Artigo
em Inglês
| IMSEAR
| ID: sea-111515
ABSTRACT
PURPOSE:
To evaluate the prognostic relevance of tumor size as determined on Magnetic Resonance Imaging (MRI) in cervical cancer. METHODS AND MATERIALS A total of 70 consecutive patients were included in the study. 15 patients underwent surgery alone (Group A), 27 patients underwent surgery followed by adjuvant radiation (Group B), 14 patients underwent concomitant chemo radiation (Group C), and 14 patients underwent radical radiation alone (Group D). External radiation was delivered followed by intra cavitary brachytherapy. Serial MRI scans were performed in all patients before and after completion of treatment on a 1.0 Tesla MRI scanner. Patients were divided into three groups based upon MR volumes 100 cc. A correlation between MR volume, FIGO stage, disease free survival (DFS) and overall survival (OS) was done. Disease free and overall survivals were calculated using Kaplan Meier survival curves according to stage, MR volume and treatment protocol.RESULTS:
In group I (MR volume 100 cc), 57% patients had stage II, 14% had stage III and 29% patients had stage IV disease. The DFS and OS did not achieve a level of statistical significance when evaluated as per protocol [DFS at p = 0.0685 and OS p = 0.3242], however a statistical significance was seen when DFS and OS were evaluated according to MR volumes [DFS, p = 0.0015 and OS, p = 0.0001].CONCLUSION:
In cervical cancer, the volume of disease as assessed on MRI may be a better prognostic indicator than FIGO staging and needs further evaluation.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prognóstico
/
Idoso de 80 Anos ou mais
/
Idoso
/
Feminino
/
Humanos
/
Imageamento por Ressonância Magnética
/
Neoplasias do Colo do Útero
/
Intervalo Livre de Doença
/
Adulto
/
Pessoa de Meia-Idade
Tipo de estudo:
Guia de Prática Clínica
/
Estudo prognóstico
Limite:
Aged80
Idioma:
Inglês
Revista:
J Cancer Res Ther
Assunto da revista:
Neoplasms
/
Therapeutics
Ano de publicação:
2005
Tipo de documento:
Artigo
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