Comparative evaluation of blood schizontocidal activity of quinine and quinidine against drug resistant rodent malaria.
Artigo
em Inglês
| IMSEAR
| ID: sea-112153
ABSTRACT
Blood schizontocidal activity of quinine and quinidine has been compared against sensitive as well as chloroquine/mefloquine/quinine resistant strains of Plasmodium berghei and a multiple resistant strain of P. yoelii nigeriensis in Swiss mice. Evaluation of results on ED50/ED90 basis has shown distinct superiority of quinidine over quinine against sensitive as well as drug resistant strain of rodent malaria.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium berghei
/
Quinidina
/
Quinina
/
Resistência a Medicamentos
/
Plasmodium yoelii
/
Avaliação Pré-Clínica de Medicamentos
/
Animais
/
Malária
/
Camundongos
Idioma:
Inglês
Ano de publicação:
1991
Tipo de documento:
Artigo
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