Anti-malarial activity of Eclipta alba against Plasmodium berghei infection in mice.
Artigo
em Inglês
| IMSEAR
| ID: sea-112199
ABSTRACT
The anti-malarial activity of Eclipta alba leaves extract was evaluated against Plasmodium'berghei ANKA strain in mice. A standard inoculum of 1 x 10(6) infected erythrocytes was used. The methanolic leaf extract (250-750 mg/kg) produced a dose-dependant chemosupression or schizontocidal effect during early and established infection and high mean survival time (m.s.t.) values particularly in the group administered 750 mg/kg/day of extract. The plant extract also exhibited repository activity. The results of the preliminary studies carried out with E. alba are encouraging, which can be exploited in malaria therapy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium berghei
/
Humanos
/
Masculino
/
Extratos Vegetais
/
Resultado do Tratamento
/
Testes de Sensibilidade Parasitária
/
Eclipta
/
Modelos Animais de Doenças
/
Animais
/
Malária
Idioma:
Inglês
Ano de publicação:
2007
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS