Glutathione and associated enzymes in toxic cataractogenesis-selenite model.
J Environ Biol
;
2006 Oct; 27(4): 733-8
Artigo
em Inglês
| IMSEAR
| ID: sea-113311
ABSTRACT
Glutathione, gamma-glutamyl cysteine synthetase (gamma -GCS) and glutathione reductase (GSH-R) activity were determined biochemically in the lens during various stages after subcutaneous administration of sodium selenite in multiple low dosages and single high dosages. The GSH concentration and gamma-GCS and GSH-R activity declined progressively after the selenite administration. The changes observed were discussed in relation to the possible role of selenite interaction with GSH and the enzymes.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Catarata
/
Feminino
/
Masculino
/
Ratos Wistar
/
Selenito de Sódio
/
Modelos Animais de Doenças
/
Relação Dose-Resposta a Droga
/
Glutamato-Cisteína Ligase
/
Glutationa
Idioma:
Inglês
Revista:
J Environ Biol
Ano de publicação:
2006
Tipo de documento:
Artigo
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