Anti-inflammatory activities of methanol extracts from various seaweed species.
J Environ Biol
;
2008 Jul; 29(4): 465-9
Artigo
em Inglês
| IMSEAR
| ID: sea-113478
ABSTRACT
Thirty-seven species of common seaweeds from the coast of Korea were screened for anti-inflammatory activity Methanol extracts of the seaweeds were tested against mouse ear edema and erythema induced by phorbol myristate acetate. At 40 mg ml(-1) of extract, edema was strongly suppressed by the seaweeds Undaria pinnatifida and Ulva linza, with relative inhibition of 85 and 84%, respectively These two seaweeds also showed the greatest suppression of erythema, with inhibition of 78 and 70%, respectively IC50 values of U. pinnatifida were 10, 15, and 18 mg ml(-1) when inflammation symptoms of edema, erythema, and blood flow, respectively were measured. The IC50 of U. linza was 20, 26, and 31 mg ml(-1) when edema, erythema, and blood flow, respectively, were measured. A linear correlation among inhibition rates of edema, erythema, and blood flow was observed with high confidence.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Alga Marinha
/
Velocidade do Fluxo Sanguíneo
/
Acetato de Tetradecanoilforbol
/
Extratos Vegetais
/
Concentração Inibidora 50
/
Metanol
/
Relação Dose-Resposta a Droga
/
Orelha
/
Edema
/
Eritema
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
J Environ Biol
Ano de publicação:
2008
Tipo de documento:
Artigo
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