Antioxidant activity of mojabanchromanol, a novel chromene, isolated from brown alga Sargassum siliquastrum.
J Environ Biol
;
2008 Jul; 29(4): 479-84
Artigo
em Inglês
| IMSEAR
| ID: sea-113610
ABSTRACT
Silica gel chromatography HPLC, El-Mass, and NMR analyses were performed in order to determine the structure obtained from the separation and refinement of the main components of an ethanol extraction of Sargassum siliquastrum, which indicated its antioxidant activity An ethanol extraction of Sargassum siliquastrum demonstrated the strongest antioxidant activities of ethyl acetate when isolated by silica gel chromatography This amounts to 84.9 +/- 1.2% of its 0.5 mg ml(-1) concentration. The thiobarbituric acid reactive substances (TBARS) measurements from 3 isolations of an HPLC separation of ethyl acetate showed that the antioxidant activity of peak 2 was the most dominant at 84.08% in a 0.5 mg ml(-1) concentration. Peak 2 was verified as a type of chromene through El-Mass and NMR analysis. Its metal sealing characteristic was low while its characteristic of TBARS and DPPH erasure indicated similar or higher levels of metal sealing characteristic. The NMR spectroscopic data was used to elucidate the structure of this new compound, which showed strong antioxidant activity in the assay.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Análise Espectral
/
Benzopiranos
/
Quelantes
/
Sequestradores de Radicais Livres
/
Cromatografia Líquida de Alta Pressão
/
Substâncias Reativas com Ácido Tiobarbitúrico
/
Sargassum
/
Etanol
/
Acetatos
/
Antioxidantes
Idioma:
Inglês
Revista:
J Environ Biol
Ano de publicação:
2008
Tipo de documento:
Artigo
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