Screening of hepatoprotective effect of a herbal mixture against CCl4 induced hepatotoxicity in Swiss albino mice.
J Environ Biol
;
2007 Apr; 28(2): 201-7
Artigo
em Inglês
| IMSEAR
| ID: sea-113637
ABSTRACT
The hepatoprotective potential of a herbal mixture was evaluated against CCl4 induced liver injury in Swiss albino mice. Liv 52, a commercially available polyherbal hepatoprotective drug was evaluated for comparison. The potential toxicity of the above herbal hepatoprotective agents was also compared. It was observed that there was a reduction in the enzyme biomarkers (Aspartate and Alanine Transaminase) of liver injury in the herbal mixture treated groups, which was similar to the reduction initiated by Liv 52. An increase in glutathione was observed in the herbal mixture treated groups and it was assumed that the herbal mixture protects the liver by virtue of its antioxidant nature along with high regeneration initiation potential. From the study it is also concluded that the herbal mixture is safer than Liv 52.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamanho do Órgão
/
Plantas Medicinais
/
Aspartato Aminotransferases
/
Glicemia
/
Nitrogênio da Ureia Sanguínea
/
Feminino
/
Masculino
/
Tetracloreto de Carbono
/
Extratos Vegetais
/
Magnoliopsida
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
J Environ Biol
Ano de publicação:
2007
Tipo de documento:
Artigo
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