Hypereosinophilic syndrome with isolated Loeffler's endocarditis: complete resolution with corticosteroids.
J Postgrad Med
;
2008 Apr-Jun; 54(2): 135-7
Artigo
em Inglês
| IMSEAR
| ID: sea-115430
ABSTRACT
Hypereosinophilic syndrome (HES) is classically defined as prolonged, unexplained peripheral eosinophilia in a patient presenting with evidence of end-organ damage. The heart is involved in two forms; endomyocardial fibrosis (Davies disease) and eosinophilic endocarditis (Loffler's endocarditis). It was first reported in 1968 by Hard and Anderson. Chusid and co-workers formulated a definition with strict criteria for the diagnosis of HES as 1) peripheral blood eosinophilia more than 1500 cells/cu mm for at least six months duration 2)signs, symptoms of end-organ (heart, lungs, gastrointestinal tract, skin, bone-marrow, brain) involvement with eosinophil tissue infiltration/injury 3) exclusion of known secondary causes of eosinophilia. We report a case of hypereosinophilic syndrome with Loffler's endocarditis, in the absence of endomyocardial fibrosis. The patient presented with a eosinophilic vegetation over the posterior leaflet of the mitral valve. There was complete resolution of the vegetation after two months of corticosteroid therapy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Masculino
/
Resultado do Tratamento
/
Corticosteroides
/
Síndrome Hipereosinofílica
/
Adulto
/
Diagnóstico Diferencial
/
Endocardite
/
Valva Mitral
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
J Postgrad Med
Ano de publicação:
2008
Tipo de documento:
Artigo
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