A comparative study of flurbiprofen and piroxicam in osteoarthritis.
J Postgrad Med
;
1992 Oct-Dec; 38(4): 164-6
Artigo
em Inglês
| IMSEAR
| ID: sea-115771
ABSTRACT
In this single-blind, multiple-dose study the efficacy and tolerability of flurbiprofen was compared with that of piroxicam in 60 adult patients suffering from osteoarthritis of the knee. The patients were randomly allocated to receive either flurbiprofen 100 mg twice daily or piroxicam 20 mg once daily for a period of four weeks. Clinical assessments w.r.t. pain, tenderness, stiffness, swelling and general activity of patient were carried out prior to initiation of trial therapy and thereafter at weekly intervals for four weeks. The findings were graded. Though significant improvements as compared to baseline data occurred in both the treatment groups, flurbiprofen was found to be superior to piroxicam in improving pain on movement and at rest (p < 0.05). The incidence of side effects was less in the group receiving flurbiprofen (6% compared to 47% observed with piroxicam).
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Osteoartrite
/
Dor
/
Índice de Gravidade de Doença
/
Feminino
/
Humanos
/
Masculino
/
Atividades Cotidianas
/
Método Simples-Cego
/
Piroxicam
/
Flurbiprofeno
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Inglês
Revista:
J Postgrad Med
Ano de publicação:
1992
Tipo de documento:
Artigo
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