Conceptual and methodologic challenges of assessing the short-term efficacy of Guggulu in obesity: data emergent from a naturalistic clinical trial.
J Postgrad Med
;
1995 Jan-Mar; 41(1): 5-7
Artigo
em Inglês
| IMSEAR
| ID: sea-116297
ABSTRACT
An open comparative trial was conducted in 58 adult obese patients (Body Mass Index > or = 25 kg/square metre). Group I (n = 27), non-drug, was advised diet (1200-1600 cals) and a brisk walk for 30 minutes. Group II, in addition, received Guggulu (Medohar) 1.5-3 gms/day for 30 days. Mean difference in weight loss between Guggulu and non-drug group was 0.32 kg (ns) on day 15 and 0.58 kg on day 30 (ns). The mean weight reduction in patients (> 90 kgs) was 1.92 kg (ns) and 2.25 kg (ns) higher in Guggulu group. All patients weighing > 90 kg lost weight in Guggulu group whilst 3 in non-drug group did not lose weight. Guggulu was tolerated well. The data from this pilot study suggest a synergistic diet-Guggulu interaction over 30 days in patients weighing > 90 kgs which needs to be confirmed in a large placebo controlled study.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plantas Medicinais
/
Feminino
/
Humanos
/
Masculino
/
Extratos Vegetais
/
Projetos Piloto
/
Resultado do Tratamento
/
Estatísticas não Paramétricas
/
Adulto
/
Ayurveda
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Inglês
Revista:
J Postgrad Med
Ano de publicação:
1995
Tipo de documento:
Artigo
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