Thymoma: a pathological study of 50 cases.
J Postgrad Med
;
2004 Apr-Jun; 50(2): 94-7
Artigo
em Inglês
| IMSEAR
| ID: sea-117624
ABSTRACT
BACKGROUND:
A combination of epithelial cells and lymphocytes results in a varied histomorphology of thymomas and consequent varied classification systems.AIM:
To correlate the Marino and Muller-Hermelink (MMH) classification with the invasive behaviour of thymomas. SETTING ANDDESIGN:
Retrospective analysis. MATERIALS ANDMETHOD:
Thymomas encountered in the past 21 years were re-classified with the MMH classification and correlated with Masaoka's staging and clinical presentation.RESULTS:
The thymomas formed 91% of the primary thymic epithelial tumours. Predominantly cortical thymomas (n=21) and cortical thymomas (n=22) were the common subtypes and 60% and 77% of these, respectively, were in stages II or III. Cystic change, necrosis or haemorrhage played no role in predicting invasive behaviour. Cortical epithelium correlated well with the presence of para-thymic syndromes, especially myasthenia gravis.CONCLUSION:
MMH classification is easy to apply. Cortical thymomas in stage I should be followed up for possible recurrence.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Timoma
/
Neoplasias do Timo
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Estudos Retrospectivos
/
Adolescente
/
Adulto
/
Pessoa de Meia-Idade
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
J Postgrad Med
Ano de publicação:
2004
Tipo de documento:
Artigo
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