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Testing of newly developed glycophospholipid antigen for the detection of P. falciparum malaria by laser light immunoassay in endemic and non-endemic areas.
J Vector Borne Dis ; 2003 Sep-Dec; 40(3-4): 105-8
Artigo em Inglês | IMSEAR | ID: sea-117986
ABSTRACT
A glycophospholipid (GPL) antigen isolated from Plasmodium falciparum culture supernatant has been tested for its antigenicity. Detection of malaria positive known blood samples and unknown field samples from endemic and non-endemic areas were compared. In this study laser light scattering immunoassay (LIA) was used for the detection of P. falciparum malaria. Test results of control (malaria negative samples from Surat) were compared with known positive samples and unknown malaria positive field samples. A positive correlation has been observed (97%) in falciparum positive samples from laboratory and unknown samples from endemic area (Haldwani) by LIA method using GPL antigen. From the results of the study it was found that GPL antigen has a better antigenic property and can detect almost all the cases of Pf malaria by LIA method.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Fosfolipídeos / Plasmodium falciparum / Feminino / Humanos / Masculino / Imunoensaio / Anticorpos Antiprotozoários / Malária Falciparum / Adulto / Doenças Endêmicas Tipo de estudo: Estudo diagnóstico Idioma: Inglês Revista: J Vector Borne Dis Assunto da revista: Parasitology / Tropical Medicine Ano de publicação: 2003 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Fosfolipídeos / Plasmodium falciparum / Feminino / Humanos / Masculino / Imunoensaio / Anticorpos Antiprotozoários / Malária Falciparum / Adulto / Doenças Endêmicas Tipo de estudo: Estudo diagnóstico Idioma: Inglês Revista: J Vector Borne Dis Assunto da revista: Parasitology / Tropical Medicine Ano de publicação: 2003 Tipo de documento: Artigo