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Estimating the relapse risk of Plasmodium vivax in Iran under national chemotherapy scheme using a novel method.
J Vector Borne Dis ; 2006 Dec; 43(4): 168-72
Artigo em Inglês | IMSEAR | ID: sea-118010
ABSTRACT

OBJECTIVES:

This study aimed to estimate the relapse risk of Plasmodium vivax under national chemotherapy scheme using a novel method, and assessed its pattern in Kahnooj, a malaria endemic area in Iran.

METHODS:

The authors traced repeated episodes of malaria attack between 1994 and 2001 and then, estimated the risks of secondary attack of P. vivax, classified by the species in their primary attack. It is suggested that the difference between the secondary attack rate in those who were infected by P falciparum and P. vivax in their primary attack may estimate the P. vivax relapse rate indirectly.

RESULTS:

This method showed that the relapse risk of P. vivax with in one and two years after the primary attack were 16.8 and 24.5% respectively. The risks of relapse before three or after 18 months were very low. INTERPRETATION &

CONCLUSION:

The relapse pattern of P. vivax was compatible with the dominant pattern in most of the temperate areas. In addition, the relapse risk was very close to the estimated relapse risks in clinical trials on anti-relapse drugs. Therefore, we concluded that the anti-relapse therapy in the study area was effective; also, this method may estimate the relapse risk of P. vivax accurately.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Plasmodium vivax / Recidiva / Estações do Ano / Fatores de Tempo / Humanos / Modelos de Riscos Proporcionais / Malária Vivax / Malária Falciparum / Irã (Geográfico) / Animais Tipo de estudo: Estudo de etiologia / Estudo prognóstico País/Região como assunto: Ásia Idioma: Inglês Revista: J Vector Borne Dis Assunto da revista: Parasitology / Tropical Medicine Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Plasmodium vivax / Recidiva / Estações do Ano / Fatores de Tempo / Humanos / Modelos de Riscos Proporcionais / Malária Vivax / Malária Falciparum / Irã (Geográfico) / Animais Tipo de estudo: Estudo de etiologia / Estudo prognóstico País/Região como assunto: Ásia Idioma: Inglês Revista: J Vector Borne Dis Assunto da revista: Parasitology / Tropical Medicine Ano de publicação: 2006 Tipo de documento: Artigo