Does autopsy of antenatally diagnosed malformed foetuses aid genetic counselling?
Artigo
em Inglês
| IMSEAR
| ID: sea-118418
ABSTRACT
BACKGROUND:
Many pregnancies are terminated because of ultrasonographic diagnosis of malformation in the foetus. A detailed foetal autopsy is needed to arrive at a definite diagnosis on the basis of which genetic counselling can be provided.METHODS:
Sixty-one foetuses, terminated because of antenatal diagnosis of congenital malformations by ultrasound, were autopsied. The ultrasound diagnosis was compared with the diagnosis reached after autopsy.RESULTS:
In 31 cases (51%) the autopsy provided additional findings. In 21 cases (34.4%), the autopsy changed the primary diagnosis. The revised diagnosis led to a change in the risk of recurrence in 18 cases (29.5%).CONCLUSION:
Genetic counselling depending solely on ultrasonographic foetal diagnosis may be erroneous. For appropriate genetic counselling, a detailed foetal examination should be carried out after termination in cases with ultrasonographically detected congenital malformations.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Autopsia
/
Anormalidades Congênitas
/
Feminino
/
Humanos
/
Gravidez
/
Ultrassonografia Pré-Natal
/
Aconselhamento Genético
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS