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Proprioceptive loss in leprous neuropathy: a study of 19 patients.
Neurol India ; 2008 Oct-Dec; 56(4): 450-5
Artigo em Inglês | IMSEAR | ID: sea-120295
ABSTRACT

BACKGROUND:

Leprosy presents commonly with mononeuritis multiplex, affecting mainly the exteroceptive sensations. Neuropathy with a significant afferent large fiber element is considered to be an uncommon manifestation of leprous neuropathy.

AIMS:

To evaluate the clinical and neurophysiologic aspects of a subset of patients with leprous neuropathy having clinical proprioceptive loss. SETTINGS AND

DESIGN:

Prospective study of patients with a diagnosis of peripheral neuropathy secondary to leprosy having proprioceptive loss. MATERIALS AND

METHODS:

Consecutive patients seen during a two-year period (2004 and 2005) diagnosed to have leprous neuropathy with proprioceptive abnormalities on clinical examination were included. The diagnosis of leprosy was achieved by clinical features along with positive skin biopsy, split skin smears or nerve biopsy. Their clinical and electrophysiological characteristics were studied. STATISTICAL

METHODS:

The results were analyzed using Chi-Square test. Values less than 0.05 were considered to be statistically significant . RESULTS AND

CONCLUSIONS:

We observed predominance (68.42%) of multibacillary of leprosy. Symmetrical neuropathies outnumbered mononeuritis multiplex (127). The pan sensory neuropathy had a mean duration of 24.32 months, but sometimes appeared early in the course of the disease. Areflexia and electrophysiological evidence of proximal affection was common, reflecting proximal spread of neuropathic process. Such patients have a higher incidence of developing deformities and ulcerations and they represent a vulnerable subset of patients with leprosy.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Propriocepção / Transtornos Psicomotores / Pele / Feminino / Humanos / Masculino / Hanseníase Tuberculoide / Estudos Prospectivos / Adulto / Pessoa de Meia-Idade Tipo de estudo: Estudo observacional Idioma: Inglês Revista: Neurol India Ano de publicação: 2008 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Propriocepção / Transtornos Psicomotores / Pele / Feminino / Humanos / Masculino / Hanseníase Tuberculoide / Estudos Prospectivos / Adulto / Pessoa de Meia-Idade Tipo de estudo: Estudo observacional Idioma: Inglês Revista: Neurol India Ano de publicação: 2008 Tipo de documento: Artigo