Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study.
Neurol India
;
2006 Sep; 54(3): 286-90
Artigo
em Inglês
| IMSEAR
| ID: sea-120642
ABSTRACT
OBJECTIVE:
To study the efficacy of splinting and oral steroids in the management of carpal tunnel syndrome (CTS).DESIGN:
Prospective, randomized, open-label, clinical and electrophysiological study with 3-month follow-up. MATERIALS ANDMETHODS:
Forty patients with CTS were randomly divided into splint group (N-20), wearing splint in neutral position for 4 weeks; and steroid group (N-20), who received oral prednisolone 20 mg/day for 2 weeks followed by 10 mg/day for 2 weeks. Clinical and electrophysiological evaluations were done at baseline and at 1-month and 3-month follow-up. Independent 't' test and paired 't' test were used for statistical analysis. OUTCOMEMEASURES:
Primary outcome measure was the symptom severity score and functional status score. Secondary outcome measures were median nerve sensory and motor distal latency and conduction velocity.RESULTS:
At the end of 3 months, statistically significant improvement was seen in symptom severity score and functional status score in both groups (P<0.001). Median nerve sensory distal latency and conduction velocity also improved significantly in both the groups at 3 months. Improvement in motor distal latency was significant (P=0.001) at 3 months in steroid group, while insignificant improvement (P=0.139) was observed in splint group. On comparing the clinical and electrophysiological improvement between the two groups, except for the functional status score, there was no significant difference at 3-month follow-up. Improvement in functional status score was significantly more in steroid group (P=0.03).CONCLUSION:
There was significant improvement in both groups, clinically as well as electrophysiologically, at 3 months. On comparing the efficacy of the two treatment methods, except for the functional status score, there was no significant difference between the two groups.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tempo de Reação
/
Contenções
/
Fatores de Tempo
/
Feminino
/
Humanos
/
Masculino
/
Esquema de Medicação
/
Prednisolona
/
Síndrome do Túnel Carpal
/
Administração Oral
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Neurol India
Ano de publicação:
2006
Tipo de documento:
Artigo
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