Immunogenicity of enhanced potency inactivated polio vaccine.
Indian Pediatr
;
1992 Nov; 29(11): 1353-6
Artigo
em Inglês
| IMSEAR
| ID: sea-12097
ABSTRACT
Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two doses were given at 4-week or 8-week intervals or when immunization was started at 6-7 weeks of age or later. The presence of maternal antibodies did not interfere significantly with the seroresponse to two doses of IPV-E. The study recommends that two doses of IPV-E give satisfactory seroconversion rates. Immunization can be started as early as 6 weeks age and the two doses can be given at 4 weeks interval to complete primary immunization against poliomyelitis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Poliomielite
/
Humanos
/
Vacina Antipólio de Vírus Inativado
/
Esquemas de Imunização
/
Poliovirus
/
Relação Dose-Resposta Imunológica
/
Lactente
/
Anticorpos Antivirais
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1992
Tipo de documento:
Artigo
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