Studies on skeletal muscle biopsies in endemic skeletal fluorosis.
Neurol India
;
2000 Jun; 48(2): 187-8
Artigo
em Inglês
| IMSEAR
| ID: sea-121443
ABSTRACT
Neurological manifestations of skeletal fluorosis have been attributed to compressive radiculomyelopathy. Experimental fluorosis has shown evidence of myopathic changes. Data on human muscle pathology is very scanty. This study included 22 patients with established osteofluorosis. 16 of them showed only EMG changes of neurogenic muscle disease. Histochemistry and histopathology of muscle biopsies showed features of muscle atrophy, evidenced by 'type I' atrophy and 'type I' grouping. No myopathic changes were observed. It may be concluded that the primary changes are related to the nerve, with muscle being affected secondarily. There was no evidence of any primary muscle pathology due to fluorosis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Doenças Ósseas
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Adenosina Trifosfatases
/
Músculo Esquelético
/
Adulto
/
Doenças Endêmicas
/
Intoxicação por Flúor
Idioma:
Inglês
Revista:
Neurol India
Ano de publicação:
2000
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS