Determination of Ki-67 labeling index in pituitary adenomas using MIB-1 monoclonal antibody.
Neurol India
;
2001 Jun; 49(2): 144-7
Artigo
em Inglês
| IMSEAR
| ID: sea-121610
ABSTRACT
Proliferative activity of 94 pituitary adenomas was assessed by the determination of the growth fraction, using MIB-1 monoclonal antibody in formalin fixed, paraffin embedded sections. This index was correlated with clinical and radiological evidence of invasiveness. The mean Ki-67 labeling index for all pituitary adenomas was 0.84% (range 0-17.45%). Hardy stage E tumours (1.44%) had a higher Ki-67 labeling index (LI) as compared with Hardy stage 0 tumours (0.36%). The difference in the Ki-67 labeling indices between invasive and non-invasive adenomas was not statistically significant. Hence, the Ki-67 labeling index is not a reliable indicator of invasiveness in pituitary adenomas.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Hipofisárias
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Imageamento por Ressonância Magnética
/
Adenoma
/
Criança
/
Adolescente
/
Antígeno Ki-67
Idioma:
Inglês
Revista:
Neurol India
Ano de publicação:
2001
Tipo de documento:
Artigo
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