Hepatitis in falciparum malaria.
Artigo
em Inglês
| IMSEAR
| ID: sea-124985
ABSTRACT
BACKGROUND:
Hepatocellular jaundice occurring in patients with falciparum malaria has been called as malarial hepatitis.METHODS:
We studied 95 consecutive patients admitted with falciparum malaria. Of these 20 had evidence of malarial hepatitis. Their clinical presentation, complications and response to treatment was compared with that of patients without evidence of malarial hepatitis.RESULTS:
The clinical presentation of these patients was not different from those without hepatitis. However, the incidence of complications such as renal failure (60% vs 25%; X2 = 8.47, p < 0.01), Adult Respiratory Distress Syndrome (35% vs 3%; X2 = 18.13, p < 0.001) and septicemia (20% vs 6%; X2 = 4.01, p < 0.05) was significantly higher. The mortality also was higher in the group of patients with malarial hepatitis (40% vs 17%; X2 = 4.85, p < 0.05).CONCLUSIONS:
We conclude that the presence of hepatitis in patients with falciparum malaria indicates a more severe illness with a higher incidence of complications and a poor prognosis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prognóstico
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Distribuição de Qui-Quadrado
/
Incidência
/
Adolescente
/
Malária Falciparum
/
Adulto
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1998
Tipo de documento:
Artigo
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