Characterisation of the Indian strain of duck hepatitis B virus (DHBV) and development of a carrier duck colony for antiviral drug testing.
Artigo
em Inglês
| IMSEAR
| ID: sea-125271
ABSTRACT
Duck hepatitis B virus (DHBV) infected carrier ducks serve as a useful model for testing anti-hepadnavirus drugs. This needs a well characterised duck hepatitis B virus strain. We cloned and sequenced the complete genome of duck hepatitis B virus strain of Indian origin. It was 3021 nucleotides in length and had all the recognisable open reading frames (Polymerase 20-2530 nucletides, Surface 693-1787 nucleotides and Core 2518-412). Using an inoculum of 50 microliters serum containing 1 x 10(11) virus particles/ml, we could infect 80% of one day old ducklings and develop a duck colony.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Antivirais
/
Dados de Sequência Molecular
/
Sequência de Bases
/
Vírus da Hepatite B do Pato
/
Genoma Viral
/
Infecções por Hepadnaviridae
/
Patos
/
Animais
Idioma:
Inglês
Ano de publicação:
1994
Tipo de documento:
Artigo
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