Effectiveness of montelukast in the treatment of atopic dermatitis.
Artigo
em Inglês
| IMSEAR
| ID: sea-1271
ABSTRACT
Leukotriene receptor antagonist ( montelukast) are recommended for the treatment of asthma, and have proved anecdotally successfully even in atopic dermatitis.In this open randomized clinical trial, the efficacy and safety of montelukast were assessed in the atopic dermatitis. Out of 31 enrolled patients all completed the study among which 16 in the montelukast group and 15 in the control group. No patient dropped from the study. Statistically significant SCORAD improvement (P = 0.003) was observed in montelukast group but in the control group SCORAD improvement was not statistically significant (P = 0.088).According to the patients impression pruritus was the most influenced SCORAD item by montelukast group immediately followed by sleep loss and inflammatory signs. On the contrary montelukast seemed to be completely devoid of activity on xerosis. No adverse effect of montelukast was observed in the present study.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Quinolinas
/
Feminino
/
Humanos
/
Masculino
/
Adolescente
/
Resultado do Tratamento
/
Adulto
/
Antagonistas de Leucotrienos
/
Dermatite Atópica
/
Acetatos
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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