Evaluation of antibacterial activity of different ganoderma lucidum extracts.

ABSTRACT

Bioproducts of Mushroom have multi beneficial effects for human welfare. Medicinal mushrooms are widely used as traditional medicinal ingredients for the treatment of various diseases and related health problems. Most of the medicinal extracts from mushroom are different forms of polysaccharides which strengthens the immune system with little or no side effect. Medicinal mushroom research has focused on discovery of compounds that can modulate positively or negatively the biological response of immune cells. The antimicrobial activity of various solvent extracts (40μg/ml) of Ganoderma lucidum was tested against six species of bacteria Escherichia coli (MTCC-443), Staphylococcus aureus (MTCC-737), Klebsiella pneumoniae (MTCC-2405), Bacillus subtilis (MTCC-1789) Salmonella typhi (MTCC-531) and Pseudomonas aeruginosa (MTCC-779). Acetone extract exhibited maximum antibacterial activity (31.60±0.10), while the most susceptible bacterium observed was Klebsiella pneumoniae.