Sydenham's chorea.
Indian Pediatr
;
1996 Feb; 33(2): 112-5
Artigo
em Inglês
| IMSEAR
| ID: sea-12909
ABSTRACT
OBJECTIVE:
To study the clinical profile in patients with Sydenham's chorea.DESIGN:
Prospective.SETTING:
Medical college and hospital.SUBJECTS:
Sixty cases with Sydenham's chorea, between 1988 and 1994, were studied. Of these 36 were girls; the mean age at presentation was 11.1 yr (range 7-16 yr).RESULTS:
Female predominance was apparent only after 9 years of age. There was a high familial incidence for both chorea and rheumatic fever. Generalized chorea was seen in 40 and hemichorea in 20 patients. The chorea lasted from 5 to 40 days; 13 patients had recurrent episodes. Gait disturbances, dysarthria and weakness were common. Six patients had co-existing heart disease, 4 had arthritis and one had subcutaneous nodules. A raised ESR and positive ASO titer were seen in 37 and 20 patients respectively.CONCLUSIONS:
There was an increased incidence of Sydenham's chorea after 9 years of age in girls possibly suggesting the influence of female sex hormones. A high incidence of neurologic manifestations were noted. Acute phase reactants were raised in almost half the patients. Sodium valproate, whenever used, was effective in controlling the chorea.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prognóstico
/
Febre Reumática
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Incidência
/
Estudos Prospectivos
/
Coreia
/
Adolescente
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1996
Tipo de documento:
Artigo
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