Growth inhibition of struvite crystals by the aqueous root extract of Rotula aquatica.
Indian J Biochem Biophys
;
2011 June; 48(3): 202-207
Artigo
em Inglês
| IMSEAR
| ID: sea-135321
ABSTRACT
Formation of urinary stone is a serious and debilitating problem throughout the world. In the present study, the inhibitory effect of aqueous extract of root of Rotula aquatica was investigated against struvite crystals (one of the components of urinary stone) grown in vitro using single diffusion gel growth technique. For setting the gel, sodium metasilicate solution (specific gravity 1.05) and 0.5 M aqueous solution of ammonium dihydrogen phosphate were mixed, so that the pH of the mixture could be set at 7.0. Equal amounts of supernatant solution of magnesium acetate (1.0 M) prepared with 0.0%, 0.5% and 1% concentrations of the extract were gently poured on the set gels. It was observed that the number, dimension, total mass, total volume, growth rate and depth of growth of struvite crystals decreased with the increasing extract concentrations in the supernatant solutions. The enhancement of dissolution rate and fragmentation of struvite crystals suggested potential application of the extract for inhibition of struvite type urinary stone.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamanho da Partícula
/
Fosfatos
/
Solubilidade
/
Humanos
/
Extratos Vegetais
/
Cálculos Urinários
/
Compostos de Magnésio
/
Raízes de Plantas
/
Cristalização
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
2011
Tipo de documento:
Artigo
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