Malaria and ciprofloxacin.

Ten case of uncomplicated P. failciparum were treated with ciprofloxacin 500 mg orally twice a day for 3 days. Mean parasitemia declined from 117.2 per 200 wbc before treatment to 60, 39.4, 17.3, and 2.6 per 200 wbc at 24, 48, 72, and 92 hours after the first dose of ciprofloxcin. Two cases were malaria free after 1 month follow up. No malaria complications developed during the trail. The drug was safe and well-tolerated.